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Chapter 8

Direct Methods for the Analysis of Quantum-Mechanical Tunnelling: Dihydrofolate Reductase

The catalytic power of enzymes has fascinated scientists for many decades but has long remained mysterious. The exquisite specificity and selectivity of enzymes can be explained, at least to a first approximation, by the simple lock and key model proposed more than a century ago by Emil Fischer to g...
Print publication date: 27 Mar 2009
Copyright year: 2009
Print ISBN: 978-0-85404-122-0
PDF eISBN: 978-1-84755-997-5
From the book series:
RSC Biomolecular Sciences