Metal-Ligand Cooperative Ni(II) Catalysis for One-Pot Access of Biologically Relevant Quinolines and Their Transfer Hydrogenation

Abstract

Herein, we present a square planar Ni(II) cooperative catalyst affixed by azo- and amido-based ligand that has been effectively employed for accessing highly substituted quinolines utilizing 2-aminoaryl alcohols with 2°-alcohols. Additionally, catalyst also utilized for the synthesis of 1,2,3,4-tetrahydroquinolines (1,2,3,4-THQs) by transfer hydrogenation of quinolines with borazane.