Novel Synthesis Approach of Metal-Biomolecule-Hexacyanoferrate Composite Nanofibers besides Developing a Chiral Sensing Probe

Abstract

New stable composite nanofibers of copper hexacyanoferrate (CuHCF) were synthesized by a remarkable electrochemical design method. Cu(II)-L-aspartic acid nanofibers were used as a metal biomolecule framework (MBioFs) for modifying a carbon paste electrode, and the electrochemical deposition of hexacyanoferrate from solution was done for synthesizing CuHCF nanofibers by cyclic voltammetry. This MBioFs established a solid nanocompartment including copper ions for electrodepositing, which led to in situ external template-free formation of CuHCF nanofibers. This preparation route combines the characteristics of one-dimensional nanofiber frameworks, the stereoselectivity of MBioFs, and the surprising features of the open-framework hexacynanometalates. This is a heterogeneous electrodeposition technique that represents a significant advancement in the synthesis of stable, self-template-assisted nanostructures of metal-hexacyanoferrates with tunable morphologies, moving beyond the conventional homogeneous reactions in solution phases. The redox peak of CuHCF nanofibers allows them to be used as a chiral probe due to the stereoselectivity of the Cu(II)-BioF nanofiber framework. Corresponding author* E-mail address: tashkhourian@susc.ac.ir (J. Tashkhourian) Comprehensive characterization techniques are employed to elucidate the electrochemical synthesis process and the chiral interactions. In a subsequent application, the modified electrode with Cu(II)-L-aspartic acid nanofibers was used to recognize tyrosine enantiomers, considering a difference in current signal of CuHCF during electrosynthesis with a linear range from 2.5 µM to 300.0 µM.