Glycine-mediated surface stabilization of amorphous calcium phosphate nanoparticles for biointeractive thin-film formation

Abstract

Spherical amorphous calcium phosphate (ACP) nanoparticles, including glycine molecules and K⁺ ions, were successfully synthesized. The glycine stabilized the ACP nanoparticle surfaces through the intermolecular interactions analogous to those in the α-phase crystalline state, enabling the uniform hybrid nanoparticle thin film formation and demonstrating their potential as coating nanomaterials.