Hydroxyl Proton Transfer for the Deoxygenative Reduction of Alcohols Mediated by Ph3P/ICH2CH2I

Abstract

The reductive deoxygenation of alcohols is a valuable transformation for molecular simplification, yet it typically requires external hydrogen donors. We report a hydroxyl proton transfer strategy for the deoxygenative reduction of triarylmethanols, mediated by a Ph3P/ICH2CH2I system under mild conditions. Notably, no external hydrogen source is needed; instead, utilizing only the alcoholic hydroxy hydrogen as the sole hydrogen donor.