HClO activated endoplasmic reticulum fluorescent probe for visualization of ferroptosis-mediated acute alcoholic gastric and liver injury

Abstract

We present a near-infrared (NIR) fluorescent probe (ER-HClO) for endoplasmic reticulum (ER) hypochlorous acid (HClO) detection. Using ER-HClO, we revealed an increased HClO in ferroptosis-mediated acute alcoholic gastric and liver injury models.

Supplementary files

Article information

Article type
Communication
Submitted
31 Jan 2026
Accepted
21 Feb 2026
First published
24 Feb 2026

Chem. Commun., 2026, Accepted Manuscript

HClO activated endoplasmic reticulum fluorescent probe for visualization of ferroptosis-mediated acute alcoholic gastric and liver injury

R. Wang, S. li, H. Wang, Y. Yang, M. Shi, X. Yu, P. Lei, X. Yang, S. Shuang, C. Dong and L. Fan, Chem. Commun., 2026, Accepted Manuscript , DOI: 10.1039/D6CC00671J

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