Near-Infrared Fluorescence Imaging of Vimentin Dynamic Enables Evaluation of Stroke Therapy in Live Mice
Abstract
We design a novel near-infrared fluorescent probe, Vim-NIG. For the first time, Vim-NIG successfully visualized the spatiotemporal dynamics of vimentin in the brains of stroke mice. Furthermore, we demonstrated the utility of Vim-NIG for evaluating the drug efficacy. This work provides a valuable tool for advancing ischemic stroke therapeutics.
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