Direct NF2 functionalization of ketones: a mild strategy for accessing high-performance gem-difluoroamino compounds

Abstract

The difluoroamino (NF₂) group is a highly valuable energetic moiety. This work presents a mild method for converting aromatic ketones into novel gem-difluoramino compounds using Me₄NSO₃NF₂. Their structures were confirmed by spectroscopy and crystallography. Compound 2k exhibits high thermal stability, lower sensitivity, and superior detonation performance, demonstrating its potential as a high-energy oxidizer.