Electrochemical immunosensor based on MXene-Au and Au-Ce-COF to detect methyl parathion

Abstract

A novel electrochemical immunosensor based on MXene-Au and Au-Ce-COF was constructed and applied for the ultrasensitive detection of methyl parathion (PTM). The MXene-Au nanomaterials were obtained by acid etching the precursor to obtain layered MXene, and then generating gold nanoparticles (Au NPs) in situ on the MXene surface. Au-Ce-COF was synthesized by first synthesizing Ce-COF through simple stirring under nitrogen (N2), and then Au NPs were generated by reducing HAuCl4 (chloroauric acid), and then ultrasonically synthesized to form the final material. The materials were characterized by multiple techniques with their electrochemical properties evaluated via cyclic voltammetry (CV).Electrochemical test results indicate that the fabricated sensor demonstrates outstanding electrocatalytic performance for PTM detection. In addition, the constructed sensor shows an extended linear response range (0.00475 -9.5 μg/mL), lower limit of detection (1.58 ng/mL), and the promising application in practical assays.