Metal-free Synthesis of α‑keto‑N‑acyl sulfoximines from Sulfoximine and α-Bromomethyl aryl ketones under Photoredox catalysis

Abstract

In this study, we describe a metal-free and mild strategy to prepare α‑keto‑N‑acyl sulfoximines through the reactions of sulfoximines with phenacyl bromide under green LED in the presence of eosin-Y as a photocatalyst. This protocol operates without the need for external oxidants and enables the formation of new C–O and C–N bonds. This method offers a sustainable and efficient approach for constructing valuable sulfoximine-based organic frameworks.