Issue 68, 2025
From the journal:

Chemical Communications

A bexarotene-attached Re(i) tricarbonyl complex for NADH oxidation and ROS-mediated cancer phototherapy

Rajesh Kushwaha, ORCID logo a   Virendra Singh,b   Biplob Koch ORCID logo *b  and  Samya Banerjee ORCID logo *a  

* Corresponding authors

a Department of Chemistry, Indian Institute of Technology (BHU), Varanasi, Uttar Pradesh 221005, India
E-mail: samya.chy@itbhu.ac.in

b Department of Zoology, Institute of Science, Banaras Hindu University, Varanasi, Uttar Pradesh 221005, India
E-mail: biplob@bhu.ac.in

Abstract

An axially substituted polypyridyl Re(CO)3 complex bearing bexarotene triggered caspase-3/7-mediated apoptosis in cancer cells through ROS generation and NADH photo-oxidation.

Graphical abstract: A bexarotene-attached Re(i) tricarbonyl complex for NADH oxidation and ROS-mediated cancer phototherapy

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Article information

DOI
https://doi.org/10.1039/D5CC03374H
Article type
Communication
Submitted
14 Jun 2025
Accepted
29 Jul 2025
First published
29 Jul 2025

Chem. Commun., 2025,61, 12713-12716

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A bexarotene-attached Re(I) tricarbonyl complex for NADH oxidation and ROS-mediated cancer phototherapy

R. Kushwaha, V. Singh, B. Koch and S. Banerjee, Chem. Commun., 2025, 61, 12713 DOI: 10.1039/D5CC03374H

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