Issue 27, 2024

Progress in ultrasmall ferrite nanoparticles enhanced T1 magnetic resonance angiography

Abstract

Contrast-enhanced magnetic resonance angiography (CE-MRA) plays a critical role in diagnosing and monitoring various vascular diseases. Achieving high-sensitivity detection of vascular abnormalities in CE-MRA depends on the properties of contrast agents. In contrast to clinically used gadolinium-based contrast agents (GBCAs), the new generation of ultrasmall ferrite nanoparticles-based contrast agents have high relaxivity, long blood circulation time, easy surface functionalization, and high biocompatibility, hence showing promising prospects in CE-MRA. This review aims to comprehensively summarize the advancements in ultrasmall ferrite nanoparticles-enhanced MRA for detecting vascular diseases. Additionally, this review also discusses the future clinical translational potential of ultrasmall ferrite nanoparticles-based contrast agents for vascular imaging. By investigating the current status of research and clinical applications, this review attempts to outline the progress, challenges, and future directions of using ultrasmall ferrite nanoparticles to drive the field of CE-MRA into a new frontier of accuracy and diagnostic efficacy.

Graphical abstract: Progress in ultrasmall ferrite nanoparticles enhanced T1 magnetic resonance angiography

Article information

Article type
Review Article
Submitted
12 Apr 2024
Accepted
28 May 2024
First published
11 Jun 2024

J. Mater. Chem. B, 2024,12, 6521-6531

Progress in ultrasmall ferrite nanoparticles enhanced T1 magnetic resonance angiography

M. Liu, Q. Feng, H. Zhang, Y. Guo and H. Fan, J. Mater. Chem. B, 2024, 12, 6521 DOI: 10.1039/D4TB00803K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements