Issue 33, 2024

Innovative approaches to wound healing: insights into interactive dressings and future directions

Abstract

The objective of this review is to provide an up-to-date and all-encompassing account of the recent advancements in the domain of interactive wound dressings. Considering the gap between the achieved and desired clinical outcomes with currently available or under-study wound healing therapies, newer more specific options based on the wound type and healing phase are reviewed. Starting from the comprehensive description of the wound healing process, a detailed classification of wound dressings is presented. Subsequently, we present an elaborate and significant discussion describing interactive (unconventional) wound dressings. Latter includes biopolymer-based, bioactive-containing and biosensor-based smart dressings, which are discussed in separate sections together with their applications and limitations. Moreover, recent (2–5 years) clinical trials, patents on unconventional dressings, marketed products, and other information on advanced wound care designs and techniques are discussed. Subsequently, the future research direction is highlighted, describing peptides, proteins, and human amniotic membranes as potential wound dressings. Finally, we conclude that this field needs further development and offers scope for integrating information on the healing process with newer technologies.

Graphical abstract: Innovative approaches to wound healing: insights into interactive dressings and future directions

Article information

Article type
Review Article
Submitted
10 Dec 2023
Accepted
29 May 2024
First published
06 Jun 2024

J. Mater. Chem. B, 2024,12, 7977-8006

Innovative approaches to wound healing: insights into interactive dressings and future directions

R. Yadav, R. Kumar, M. Kathpalia, B. Ahmed, K. Dua, M. Gulati, S. Singh, P. J. Singh, S. Kumar, R. M. Shah, P. K. Deol and I. P. Kaur, J. Mater. Chem. B, 2024, 12, 7977 DOI: 10.1039/D3TB02912C

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