Issue 47, 2024
From the journal:

Organic & Biomolecular Chemistry

Cu(ii)-catalyzed synthesis of N-sulfonated quinolin-2(1H)-one-3-carboxamides†

Xue Chen,a   Shi-Jie Fang,b   Quan Zhou, ORCID logo *ac   Wei Huang,a   Qiu-Lan Liua  and  Lei Wang ORCID logo *ac  

* Corresponding authors

a School of Pharmaceutical Sciences, Taizhou University, Taizhou, Zhejiang, P. R. China
E-mail: qzhou@tzc.edu.cn

b School of Pharmaceutical and Chemical Engineering, Taizhou University, Taizhou, Zhejiang, P. R. China

c Advanced Research Institute, Taizhou University, Taizhou, Zhejiang 318000, P. R. China

Abstract

Herein, N–N bond cleavage of sulfonylhydrazides was observed and applied in the synthesis of N-sulfonated quinolin-2-(1H)-one-3-carboxamides. More than 30 examples were forged in 52%–97% yields. Further transformation delivered a 3,4-dihydro-quinolin-2(1H)-one derivative.

Graphical abstract: Cu(ii)-catalyzed synthesis of N-sulfonated quinolin-2(1H)-one-3-carboxamides

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Article information

DOI
https://doi.org/10.1039/D4OB01071J
Article type
Communication
Submitted
28 Jun 2024
Accepted
02 Sep 2024
First published
20 Nov 2024

Org. Biomol. Chem., 2024,22, 9209-9213

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Cu(II)-catalyzed synthesis of N-sulfonated quinolin-2(1H)-one-3-carboxamides

X. Chen, S. Fang, Q. Zhou, W. Huang, Q. Liu and L. Wang, Org. Biomol. Chem., 2024, 22, 9209 DOI: 10.1039/D4OB01071J

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