Isomeric double-cavity coordination cages: to encapsulate or not to encapsulate the guest

Abstract

A series of three isomeric double-cavity discrete coordination cages with Pd₃L₄ formulation, constructed from Pd(II) and regioisomeric tris-monodentate ligands, are compared for binding pyrazine N,N′-dioxide. Two of the isomeric cages efficiently encapsulated the guest in both cavities, whereas one of the isomers rejected the guest completely.