We developed a modification-facilitated exfoliation strategy for the one-step preparation of ultrathin 2D functionalized covalent organic framework nanosheets (COF NSs). Hyaluronic acid-functionalized ultrathin porphyrin COF NSs (about 5–8 nm) with enhanced reactive oxygen species (ROS) generation effect were readily prepared for tumor-targeted photodynamic therapy.
P. Gao, R. Wei, B. Cui, X. Liu, Y. Chen, W. Pan, N. Li and B. Tang, Chem. Commun., 2021, 57, 6082 DOI: 10.1039/D1CC02124A
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