Rapid prototyping of functional acoustic devices using laser manufacturing

Xiang Zhang; Rosa Son; Yen-Ju Lin; Alexi Gill; Shilin Chen; Tong Qi; David Choi; Jing Wen; Yunfeng Lu; Neil Y. C. Lin; Pei-Yu Chiou

doi:10.1039/D2LC00725H

Rapid prototyping of functional acoustic devices using laser manufacturing†

Xiang Zhang,

‡^a Rosa Son,‡^a Yen-Ju Lin,^b Alexi Gill,^a Shilin Chen,^cd Tong Qi,^cd David Choi,^a Jing Wen,^d Yunfeng Lu,

^c Neil Y. C. Lin^aef and Pei-Yu Chiou*^a

Author affiliations

* Corresponding authors

^a Department of Mechanical and Aerospace Engineering, University of California at Los Angeles, USA
E-mail: pychiou@g.ucla.edu

^b Department of Electrical and Computer Engineering, University of California at Los Angeles, USA

^c Department of Chemical and Biomolecular Engineering, University of California at Los Angeles, USA

^d Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine, University of California at Los Angeles, USA

^e Department of Bioengineering, University of California at Los Angeles, USA

^f Institute for Quantitative and Computational Biosciences, University of California at Los Angeles, USA

Abstract

Acoustic patterning of micro-particles has many important biomedical applications. However, fabrication of such microdevices is costly and labor-intensive. Among conventional fabrication methods, photo-lithography provides high resolution but is expensive and time consuming, and not ideal for rapid prototyping and testing for academic applications. In this work, we demonstrate a highly efficient method for rapid prototyping of acoustic patterning devices using laser manufacturing. With this method we can fabricate a newly designed functional acoustic device in 4 hours. The acoustic devices fabricated using this method can achieve sub-wavelength, complex and non-periodic patterning of microparticles and biological objects with a spatial resolution of 60 μm across a large active manipulation area of 10 × 10 mm².

This article is part of the themed collection: Lab on a Chip HOT Articles 2022

Lab on a Chip

Rapid prototyping of functional acoustic devices using laser manufacturing†

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