Issue 2, 2022

Effects of carbamazepine in aquatic biota

Abstract

Carbamazepine (CBZ) is one of the most common pharmaceuticals found in the aquatic environment. Here, we reviewed studies in aquatic animals highlighting that CBZ affected ROS homeostasis but also the neuroendocrine system, cell viability, immunity, reproduction, feeding behavior and growth. Notably, the acetylcholinesterase activity was modified by concentrations of the order of ng L−1 CBZ. At ≥10 μg L−1, data pointed that CBZ triggered the production of ROS, modifying the activity of antioxidant enzymes and produced a significant cellular stress at concentrations ≥100 μg L−1. However, the response appeared species-, organ- and time-dependent, and was impacted by different experimental conditions and the origin of animals. In this context, this review discusses the available data and proposes future research priorities.

Graphical abstract: Effects of carbamazepine in aquatic biota

Article information

Article type
Critical Review
Submitted
06 Aug 2021
Accepted
22 Dec 2021
First published
04 Jan 2022

Environ. Sci.: Processes Impacts, 2022,24, 209-220

Effects of carbamazepine in aquatic biota

H. Baali and C. Cosio, Environ. Sci.: Processes Impacts, 2022, 24, 209 DOI: 10.1039/D1EM00328C

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