Issue 99, 2022

An ‘AND’-based ratiometric fluorescence probe for the sequential detection of biothiols and hypochlorous acid

Abstract

An ‘AND’-based ratiometric fluorescence probe for the sequential detection of biothiols and hypochlorous acid was developed. FRET was observed only when RSHClO reacted with biothiols before reacting with hypochlorous acid, a phenomenon that has been confirmed in aqueous solutions and cells. This feature enables the probe to mimic biological processes and is particularly suitable for imaging oxidizing and reducing substances that cannot coexist.

Graphical abstract: An ‘AND’-based ratiometric fluorescence probe for the sequential detection of biothiols and hypochlorous acid

Supplementary files

Article information

Article type
Communication
Submitted
25 Oct 2022
Accepted
16 Nov 2022
First published
18 Nov 2022

Chem. Commun., 2022,58, 13720-13723

An ‘AND’-based ratiometric fluorescence probe for the sequential detection of biothiols and hypochlorous acid

H. Zhang, L. Li, L. Shi, S. Chen, K. Li and X. Yu, Chem. Commun., 2022, 58, 13720 DOI: 10.1039/D2CC05782D

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