Issue 60, 2015
From the journal:

Chemical Communications

Ag nanocluster-based label-free catalytic and molecular beacons for amplified biosensing†

Liang Gong,a   Hailan Kuai,a   Songlei Ren,a   Xu-Hua Zhao,*b   Shuang-Yan Huan,a   Xiao-Bing Zhang*a  and  Weihong Tana  

* Corresponding authors

a Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China
E-mail: xbzhang@hnu.edu.cn

b Department of Biochemistry and Molecular Biology, Shanxi Medical University, Taiyuan, Shanxi 030001, China
E-mail: zxh_snow521@sina.com

Abstract

By employing DNAzyme as a recognition group and amplifier, and DNA-stabilized silver nanoclusters (DNA/AgNCs) as signal reporters, we reported for the first time a label-free catalytic and molecular beacon as an amplified biosensing platform for highly selective detection of cofactors such as Pb2+ and L-histidine.

Graphical abstract: Ag nanocluster-based label-free catalytic and molecular beacons for amplified biosensing

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Article information

DOI
https://doi.org/10.1039/C5CC04442A
Article type
Communication
Submitted
30 May 2015
Accepted
18 Jun 2015
First published
18 Jun 2015

Chem. Commun., 2015,51, 12095-12098

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Ag nanocluster-based label-free catalytic and molecular beacons for amplified biosensing

L. Gong, H. Kuai, S. Ren, X. Zhao, S. Huan, X. Zhang and W. Tan, Chem. Commun., 2015, 51, 12095 DOI: 10.1039/C5CC04442A

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