Issue 5, 2021

Acridinium benzoates for ratiometric fluorescence imaging of cellular viscosity

Abstract

A series of fluorescent molecular rotors, acridinium benzoates (Acr-A,B,C,D), were designed for ratiometrically monitoring cellular viscosity. High sensitivity to viscosity was observed in probe Acr-A with an insignificant steric effect in the acridinium nitrogen. Acr-A was employed to distinguish cancer cells from normal cells and track the dynamics of viscosity during cellular apoptosis.

Graphical abstract: Acridinium benzoates for ratiometric fluorescence imaging of cellular viscosity

Supplementary files

Article information

Article type
Communication
Submitted
03 Dec 2020
Accepted
11 Jan 2021
First published
11 Jan 2021

Analyst, 2021,146, 1538-1542

Acridinium benzoates for ratiometric fluorescence imaging of cellular viscosity

M. Wen, C. Li, M. Zhang, Y. Sun, F. Liu, X. Cui and Y. Shan, Analyst, 2021, 146, 1538 DOI: 10.1039/D0AN02321C

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