Issue 54, 2023

Activatable BODIPY-chromene NIR-II probes with small spectral crosstalk enable high-contrast in vivo bioimaging

Abstract

Herein, we design a novel crossbreeding dye (BC-OH) within the second near-infrared (NIR-II) window based on BODIPY and chromene chromophores. BC-OH can serve as a platform to construct activatable NIR-II probes with small spectral crosstalk, thereby making a breakthrough in imaging in vivo H2O2 fluctuation in an APAP-induced liver injury model with high signal-to-background ratio.

Graphical abstract: Activatable BODIPY-chromene NIR-II probes with small spectral crosstalk enable high-contrast in vivo bioimaging

Supplementary files

Article information

Article type
Communication
Submitted
14 Apr 2023
Accepted
18 May 2023
First published
29 May 2023

Chem. Commun., 2023,59, 8388-8391

Activatable BODIPY-chromene NIR-II probes with small spectral crosstalk enable high-contrast in vivo bioimaging

L. Zhang, C. Yan, Y. Zhang, D. Ma, J. Huang, Z. Zhao, Y. Tao, C. Liu, J. Li, W. Zhu and Z. Guo, Chem. Commun., 2023, 59, 8388 DOI: 10.1039/D3CC01742G

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