Issue 48, 2023
From the journal:

Chemical Communications

A covalent organic framework-based nanoreactor for enhanced photothermal therapy via inhibiting intracellular heat defense systems†

Yan-An Li, ORCID logo ‡*a   Jing-Jing Wan,‡a   Wen-Yan Li,a   Qun Guan ORCID logo a  and  Yu-Bin Dong ORCID logo *a  

* Corresponding authors

a College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Normal University, Jinan 250014, P. R. China
E-mail: yananli@sdnu.edu.cn, yubindong@sdnu.edu.cn

Abstract

Herein, we report an indocyanine green (ICG)-decorated and glucose oxidase (GOx)-loaded nanoscale composite COF material via a stepwise post-synthetic modification. The obtained GOx@COF-ICG can achieve synergistic inhibition of intracellular heat defense systems through starvation therapy to enhance photothermal therapy of tumors.

Graphical abstract: A covalent organic framework-based nanoreactor for enhanced photothermal therapy via inhibiting intracellular heat defense systems

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Article information

DOI
https://doi.org/10.1039/D3CC01153D
Article type
Communication
Submitted
08 Mar 2023
Accepted
22 May 2023
First published
22 May 2023

Chem. Commun., 2023,59, 7463-7466

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A covalent organic framework-based nanoreactor for enhanced photothermal therapy via inhibiting intracellular heat defense systems

Y. Li, J. Wan, W. Li, Q. Guan and Y. Dong, Chem. Commun., 2023, 59, 7463 DOI: 10.1039/D3CC01153D

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