Issue 26, 2022
From the journal:

Chemical Communications

Selective detection of ozone in inflamed mice using a novel activatable chemiluminescent probe†

Yurong Feng,a   Shuai Xu,*a   Zhi-Ling Song, ORCID logo b   Tian-Bing Ren, ORCID logo a   Shuang-Yan Huan, ORCID logo *a   Lin Yuan ORCID logo a  and  Xiao-Bing Zhang ORCID logo a  

* Corresponding authors

a State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical En-gineering, Hunan University, Changsha 410082, P. R. China
E-mail: shuaixu@hnu.edu.cn, syhuan@hnu.edu.cn

b Key Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science, MOE, Shandong Key Laboratory of Biochemical Analysis, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China

Abstract

We report here an activatable chemiluminescent probe CL-O3 for the high-contrast imaging of O3in vivo. CL-O3 exhibited a high selectivity toward O3 and was able to evaluate the degree of inflammation in mice by detecting endogenous O3 levels in acute inflamed mice.

Graphical abstract: Selective detection of ozone in inflamed mice using a novel activatable chemiluminescent probe

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Article information

DOI
https://doi.org/10.1039/D2CC00359G
Article type
Communication
Submitted
19 Jan 2022
Accepted
03 Mar 2022
First published
04 Mar 2022

Chem. Commun., 2022,58, 4184-4187

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Selective detection of ozone in inflamed mice using a novel activatable chemiluminescent probe

Y. Feng, S. Xu, Z. Song, T. Ren, S. Huan, L. Yuan and X. Zhang, Chem. Commun., 2022, 58, 4184 DOI: 10.1039/D2CC00359G

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