Issue 32, 2020

Stimuli-responsive polymer-based systems for diagnostic applications

Abstract

Stimuli-responsive polymers exhibit properties that make them ideal candidates for biosensing and molecular diagnostics. Through rational design of polymer composition combined with new polymer functionalization and synthetic strategies, polymers with myriad responsivities, e.g., responses to temperature, pH, biomolecules, CO2, light, and electricity can be achieved. When these polymers are specifically designed to respond to biomarkers, stimuli-responsive devices/probes, capable of recognizing and transducing analyte signals, can be used to diagnose and treat disease. In this review, we highlight recent state-of-the-art examples of stimuli-responsive polymer-based systems for biosensing and bioimaging.

Graphical abstract: Stimuli-responsive polymer-based systems for diagnostic applications

Article information

Article type
Review Article
Submitted
02 Mar 2020
Accepted
06 Jul 2020
First published
03 Aug 2020

J. Mater. Chem. B, 2020,8, 7042-7061

Stimuli-responsive polymer-based systems for diagnostic applications

T. Shu, L. Hu, Q. Shen, L. Jiang, Q. Zhang and M. J. Serpe, J. Mater. Chem. B, 2020, 8, 7042 DOI: 10.1039/D0TB00570C

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