Reducing-agent-free facile preparation of Rh-nanoparticles uniformly anchored on onion-like fullerene for catalytic applications

Herein we report a very simple ‘mix and heat’ synthesis of a very fine Rh-nanoparticle loaded carbon fullerene-C60 nanocatalyst (Rh(0)NPs/Fullerene-C60) for the very first time. The preparation method used no reducing agent and capping agent to control the morphology of the nanocatalyst. Transmission electron microscopy (TEM) results confirmed the uniform decoration of small Rh-nanoparticles on the surface of fullerene-C60. The Rh-content in Rh(0)NPs/Fullerene-C60 was found to be 2.89 wt%. The crystalline properties of Rh(0)NPs/Fullerene-C60 were studied by X-ray diffraction (XRD). The metallic state of Rh-nanoparticles in Rh(0)NPs/Fullerene-C60 was confirmed by X-ray photoemission spectroscopy (XPS). Raman results depicted good interaction between Rh-nanoparticles and fullerene-C60. To our delight, the present Rh(0)NPs/Fullerene-C60 showed excellent catalytic activity in the reduction of 4-nitrophenol with NaBH4 in water. Very high kapp, k′ and TOF values of 82.14 × 10−3 min−1, 4107 × 10−3 min−1 and 138 min−1, respectively, were calculated for the Rh(0)NPs/Fullerene-C60 catalyzed reduction of 4-nitrophenol. To the best of our knowledge, this is the most efficient fullerene-based nanocatalyst for the rapid reduction of 4-nitrophenol reported to date. Moreover, the catalytic activity of Rh(0)NPs/Fullerene-C60 was also tested towards Suzuki cross-coupling reactions. Reusability of the Rh(0)NPs/Fullerene-C60 was also tested.


Introduction
Carbon nanomaterials such as graphene oxide (GO), carbon nanotubes (CNTs), carbon dots (CDs), carbon nanobers (CNFs), and nano-diamond are demonstrated to be the most suitable platform (support material) for the decoration of catalytic metal-nanoparticles. 1,2 High activity, easy recovery and reusability of such metal-nanoparticles based carbon nanocomposites are found to be signicantly inuenced by the nature of support material used. 3 Indeed, unique structure, ne size, huge surface area and exceptional electrochemical properties make carbon nanocomposites suitable candidates for widespread applications. 4 In particular, the role of carbon nanocomposites in heterogeneous catalysis is demonstrated to be highly exceptional. For example, Sen et al. 5 prepared thiocarbamide-functionalized graphene oxide (TC@GO) supported Rh/Pt nanocomposites (RhPt/TC@GONPs) via a facile method. They found that the RhPt/TC@GONPs is a highly promising catalyst for the Knoevenagel condensation to benzylidenemalononitrile derivatives of aryl aldehydes. Similarly, Gunbatar and co-workers 6 reported CNTs/Rh-nanoparticles catalyst for hydrolytic dehydrogenation of dimethylamineborane at room temperature. Carbon nanobers (CNFs) are also widely used as support for the immobilization of active catalytic materials. For instance, Motoyama et al., 7 decorated Rhnanoparticles on carbon nanobers (CNFs) to obtain a highly efficient nanocatalyst (Rh/CNF-T) for arene hydrogenation. The Rh/CNF-T showed high catalytic activity in the hydrogenation of arene under mild conditions in high turnover numbers (TOFs) without leaching of Rh species. Alike, numerous carbon nanocomposites (for example: Fe 2 O 3 /NGr@C, 8 SWCNT-Met/Pd 0 , 9 Pt/ Au/BDD, 10 Pd@C-dot, 11 and Ir/CNFs 12 ) are reported as highly efficient catalysts for various industrially important organic reactions. Alike other carbon materials, buckminsterfullerene (carbon fullerene-C60) has also been widely used as key material in diverse applications in chemistry, biology, and nanoscience. 13,14 The fullerene-C60 incorporated nanosized particles (transition metals or semiconductor) were found to exhibit excellent results in the elds of energy, sensor and catalysis. 15 For instance, Islam et al., 16 prepared fullerene-C60 stabilized Au nanoparticles supported on titanium dioxide and used as an efficient catalyst for the degradation of methyl orange and reduction of 4-nitrophenol. Similarly, Ko and co-workers 17 demonstrated catalytic reduction of 4-nitrophenol using Aunanoparticle/Fullerene-C60 composites. In spite of that only a limited number of papers published on the carbon fullerene-C60 supported transition metal nanoparticles for catalytic organic conversions. Hence, the development of highly efficient fullerene-C60 based nanocomposites for the catalytic organic reaction is indeed very essential. Rhodium (Rh) is known for its outstanding catalytic properties, particularly, in hydrogenation, electro-oxidation and coupling reactions. [18][19][20] Generally, due to strong resistance to etching of acid/base and heat, the Rh-based catalysts are stable and more versatile in catalytic reaction even under harsh reaction conditions. 21,22 Hence, signicant efforts have been taken for developing simple and efficient wet-chemistry approaches for the preparation of Rh-nanostructures with unique size and shape. [18][19][20][21][22][23] Jiang et al., 24 reported an efficient chemical reduction method for the preparation of mesoporous Rh nanostructures. Recently, Kang and co-workers 25 obtained three types of Rhbased nanostructures (nanoshells, nanoframes, and porous nanoplates) through an inverse-directional galvanic replacement reaction. However, most of these preparation methods oen involve expensive process and toxic reagents. Recently, our group developed a very simple 'mix and heat' method for the preparation of various highly active metal-nanoparticles based carbon nanocomposites for organic reaction. [26][27][28][29][30] We found that the method is not only efficient but also uses no reducing or capping agent to control the size and shape of metal-nanostructures. We believed that the decoration of Rhnanoparticles on carbon fullerene-C60 would result in highly active nanocomposite for catalytic applications. Herein, highly active Rh-nanoparticles anchored carbon fullerene-C60 nanocomposite (Rh(0)NPs/Fullerene-C60) was successfully prepared by a very simple 'mix and heat' method using water. The resultant Rh(0)NPs/Fullerene-C60 catalyst was characterized by means X-ray photoemission spectroscopy (XPS), Raman, X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FT-IR), scanning electron microscopy with energy dispersive spectroscopy (SEM-EDS), atomic force microscope (AFM) and transmission electron microscopy (TEM). Aer being characterized, the Rh(0)NPs/Fullerene-C60 was used as catalyst for the reduction of 4-nitrophenol and Suzuki-Miyaura reaction. In fact, both these reactions (reduction and coupling reactions) are very important in organic chemistry and the catalytic products prepared via these reactions are found to be highly useful in pharmaceuticals and ne chemicals. 31,32 Reusability of the Rh(0) NPs/Fullerene-C60 was also studied. Mechanism has also been proposed for the Rh(0)NPs/Fullerene-C60 catalyzed 4-nitrophenol reduction of Suzuki-Miyaura cross coupling reaction.

Preparation of Rh(0)NPs/Fullerene-C60
Most of the Rh-nanostructures are produced by wet-chemical synthesis using toxic reducing or capping agents. [18][19][20][21][22][23] To our delight, the present preparation method involves no capping or reducing agents. In a typical 'mix and heat' preparation of Rh(0) NPs/Fullerene-C60, 500 mg of carbon fullerene-C60 was mixed with 80 mg of Rh(acac) 3 dissolved in 20 mL of double distilled water and the mixture was stirred at 80 C for 6 h. Then the water from the above reaction mixture was removed by heating the solution at 100 C for several hours. The resultant solid mixture of fullerene-C60/Rh(acac) 3 was mixed well using mortar and pestle for 10 min. Finally, the obtained homogenous mixture of fullerene-C60/Rh(acac) 3 was calcinated under argon atmosphere at 150 C for 2 h. The resultant solid catalyst (Rh(0) NPs/Fullerene) was characterized by means of various spectroscopic and microscopic techniques, and used for catalytic applications. Scheme 1 shows the schematic illustration for the preparation of Rh(0)NPs/Fullerene-C60.

Characterization
TEM (JEOL JEM 2100F) instrument was operated at accelerating voltage of 200 kV to record the surface morphology of Rh(0)NPs/ Fullerene-C60. Park System model XE100 AFM was used to capture the 1D and 3D AFM images of fullerene-C60 and Rh(0) NPs/Fullerene-C60 in a non-contact mode. Metal loading and elements present in Rh(0)NPs/Fullerene-C60 were determined by EDS analysis (Hitachi 3000H SEM). Crystalline property of samples was studied by using XRD (Rigaku Ultima XRD) and the Raman spectra were recorded on LabRam ARAMIS IR2. Chemical property of the fullerene-C60 and Rh(0)NPs/Fullerene-C60 was investigated by XPS analysis using a Kratos Axis-Ultra DLD, Kratos Analytical Ltd, Japan. FTIR (IR Prestige-21, Shimadzu, Japan) spectra were recorded for both fullerene-C60 and Rh(0)NPs/Fullerene-C60. Catalytic performance of fullerene-C60 and Rh(0)NPs/Fullerene-C60 was studied by UV-vis (Shimadzu UV-2600 spectrophotometer) spectra and GC analysis (Shimadzu-2010 gas chromatograph). NMR (400 MHz Bruker spectrometer) spectra were recorded for the catalytic products.

Procedure for reduction of 4-nitrophenol
Catalytic activity of fullerene-C60 and Rh(0)NPs/Fullerene-C60 was studied towards reduction of 4-nitrophenol. Initially, best reaction conditions were found out. In a typical reduction of 4nitrophenol, 4 mL of 0.015 M NaBH 4 , 80 mL of 0.01 M 4-nitrophenol and 0.001, 0.0015 or 0.002 mg of Rh(0)NCs/GNPs were sonicated for 15 seconds and the reaction mixture was stirred under room temperature. The progress of the reaction was checked at regular time intervals by using UV-vis spectroscopy.

Suzuki-Miyaura reaction
In a typical procedure, 183 mg of phenylboronic acid (1.5 mmol), 185 mg of 4-bromobenzaldehyde (1.0 mmol), 84 mg of potassium hydroxide and 2.5 mg of Rh(0)NPs/Fullerene-C60 were stirred in 10 mL of 1,4-dioxane/water mixture (8 mL of 1,4-dioxane and 2 mL of water) under N 2 atmosphere at 80 C for 24 h. Aer completion of the reaction, the reaction mixture was analyzed by GC and the catalytic products were extracted using hexane with help of water. Biphenyl (3ab): 1

Characterization of Rh(0)NPs/Fullerene-C60
A simple 'mix and heat' method was developed for the preparation of Rh(0)NPs/Fullerene-C60 catalyst by using carbon  This journal is © The Royal Society of Chemistry 2020 RSC Adv., 2020, 10, 2545-2559 | 2547 fullerene C60 and Rh(acac) 3 . A simple calcination of the homogenous mixture of fullerene-C60/Rh(acac) 3 under inert atmosphere at elevated temperatures successfully produced the present Rh(0)NPs/Fullerene-C60 catalyst. To our delight, water was used to obtain the uniform dispersion of Rh(0)nanoparticles on the surface of carbon fullerene-C60, and no reducing or capping agent was used. Fig. 1 shows the TEM images of Rh(0)NPs/Fullerene-C60. The size of carbon fullerene-C60 balls varied from 30 to 50 nm. It can be clearly seen from Fig. 1a-c that the onion-like carbon fullerene-C60 ball aggregates consisted of very ne Rh-nanoparticles conrming the efficient loading of Rh-nanoparticles. Surprisingly, the size (mean size $4.3 nm) and shape (spherical) of the Rhnanoparticles were seen to be quite uniform and the Rhnanoparticles were uniformly dispersed on the surface of fullerene-C60 balls. Although there is no capping agent was used, still the shape and size of the Rh-nanoparticles supported on fullerene-C60 balls could be controlled. Fig. 1e depicts the particle size distribution of Rh-nanoparticles in Rh(0)NPs/ Fullerene-C60 which showed that the size of Rh-nanoparticles varied from 0.1 nm to 8 nm with mean size of 4.3 nm. The fresh fullerene-C60 and Rh(0)NPs/Fullerene-C60 were further analyzed by AFM. Fig. 2a-d shows the 1D and 3D AFM proles of fullerene-C60 before and aer Rh(0)-nanoparticles loading. The 1D and 3D AFM proles of fresh fullerene-C60 showed smooth surface morphology with mean roughness (R q ) values of 91 nm. However, Rh-nanoparticles loaded fullerene-C60 showed R q value of 27 nm conrming the high surface roughness due to the uniform decoration of Rh-nanoparticles on the fullerene-C60 surface. Moreover, the mean size of Rh-nanoparticles was calculated to be around 3.9 nm which aggress well with the TEM observations. To further the surface area per unit mass (S) of Rh(0)-nanoparticles was calculated by using the equation S ¼ 6000/(r Â d), where d is the mean diameter of Rh(0)NPs (4.3 nm), and r is the density of Rh (12.41 g cm À3 ). 29 The S value of Rh(0)NPs/Fullerene-C60 was calculated to be 112.44 m 2 g À1 .
To further SEM-EDS analysis was performed to nd out the elements present in Rh(0)NCs/GNPs catalyst (Fig. 3). The SEM image shows the globular shape of carbon fullerene-C60 ball aggregates consisted of Rh-nanoparticles. Interestingly, the EDS results conrmed the presence of only C, O and Rh elements; indicate the high purity of Rh(0)NCs/GNPs catalyst and reliability of the present preparation method. The loading of Rh in Rh(0)NCs/GNPs was determined to be 2.89 wt%. The EDS wt% of C and O was 85.66 and 11.45, respectively. The elemental mapping of C, O and Rh conrms the homogenous dispersion of Rh-nanoparticles in Rh(0)NCs/GNPs catalyst.   33 Similarly, the Rh-nanoparticles loaded fullerene-C60 demonstrates three foremost peaks at around 2q ¼ 10.7 , 2q ¼ 17.6 , and 2q ¼ 20.6 which clearly indicate that the loading of Rh-nanoparticles did not signicantly alter the crystal structure. 33 It is believed that the relatively higher electron mobility of fcc structure of the present Rh(0)NPs/Fullerene-C60 would show enhanced catalytic activity. Surprisingly, the XRD pattern of Rh(0)NPs/Fullerene-C60 showed no peaks correspond to the Rh-metal. The absence of Rh-metal peaks is mainly due to the small particle sizes and high degree of dispersion. 26 Moreover, the peak broadening and overlapping maybe due to the partial structural imperfection or transformation of fcc crystals by the decoration of Rh-nanoparticles on fullerene-C60.
The structural characterization of fullerene-C60 before and aer Rh-loading was further studied by Raman spectroscopy (Fig. 5). The Raman spectrum of fresh fullerene-C60 showed several lines at 275, 430, 492, 710, 771, 1425, 1467 and 1571 cm À1 , in which the most intense and signicant lines were seen at 492 (A g (1) mode) and 1467 cm À1 (A g (2) mode or 'pentagonal pinch mode'). 34 The D band represents the presence of sp 3 carbons or structural disorder. The G-band at around 1571 cm À1 resembles E 2g mode of sp 2 -hybridized This journal is © The Royal Society of Chemistry 2020 RSC Adv., 2020, 10, 2545-2559 | 2549 carbon matrix or graphitic domains. Alike fresh fullerene-C60, the Raman spectrum of Rh(0)NPs/Fullerene-C60 presented several lines with two dominate peaks at 497 and 1452 cm À1 correspond to A g (1) mode and A g (2) mode or 'pentagonal pinch mode', respectively. In comparison to fresh fullerene-C60, the Raman lines of Rh(0)NPs/Fullerene-C60 at 497 and 1452 cm À1 were found to be shied to lower frequency (Fig. 5b). In addition, the H g (8) line at 1571 cm À1 of fresh fullerene-C60 shied to 1599 cm À1 in the Rh(0)NPs/Fullerene-C60 sample. This phenomenon is due to the strong interaction of Rhnanoparticles with the fullerene-C60. 29 In general, the covalent interaction of foreign species with fullerene-C60 would oen increases the sp 3 -hybridized carbon atoms (increase in the D-band intensity can be seen). In the present case, the Rhnanoparticles may be physically attached on the surface of fullerene-C60.
XPS spectra of fullerene-C60 and Rh(0)NPs/Fullerene-C60 are presented in Fig. 6. It can be seen that both fresh fullerene-C60 and Rh-loaded fullerene-C60 demonstrate two dominate peaks at 283.5 and 531.5 eV correspond to C 1s and O 1s peaks, respectively. The intense C 1s and O 1s peaks clearly show the existence of sp 2 and sp 3 carbon along with the surface bound oxygen groups. 27 Fig. 6b and c presents the deconvoluted C 1s and O 1s XPS peaks of Rh(0)NPs/Fullerene-C60. The deconvolation of C 1s peak resulted in four peaks at 283.9, 284.3 and 285.6 eV correspond to C-C/C]C, C-OH and C-O-C groups, respectively. 26,27 The possible four deconvoluted O 1s peaks (530.8, 531.2, 531.7, 532.5 eV) also conrmed the presence of oxygen groups in the Rh(0)NPs/Fullerene-C60. 30 In general, due to highly hydrophobic in nature, it is very challenging to achieve good dispersion of fullerene-C60 in aqueous and organic solvents. In the present case, the presence of oxygen groups could assist for the better dispersion of Rh(0)NPs/Fullerene-C60 in a wide range of reaction mediums. In comparison to the fresh fullerene-C60, the XPS spectrum of Rh(0)NPs/Fullerene-C60 showed new peaks at Rh 3d region (321-303 eV), indicating the successful loading of Rh-nanoparticles. Moreover, the Rh 3d 3/2 peak at 312.8 eV and the Rh 3d 5/2 peak at 308.3 eV showed the metallic nature of the Rh-nanoparticles. 35 To further FT-IR spectra were also taken for the fullerene-C60 and Rh(0)NPs/ Fullerene-C60 (see Fig. S1 in ESI †). The fresh carbon fullerene-C60 showed a broad peak at 3375 cm À1 which obviously conrms the presence of -OH groups. Moreover, three other characteristic peaks at 1570 cm À1 (C]C), 1410 cm À1 (C-OH), 1175 cm À1 and 1040 cm À1 (C-O) were also noticed. 36 In comparison to the fresh carbon fullerene-C60, the FT-IR peak positions of Rh(0)NPs/Fullerene-C60 were noticed to be significantly shied either to lower or higher frequency region. This phenomenon is may be due to the decoration of Rhnanoparticles on the fullerens-C60.

Catalytic reduction of 4-nitrophenol
The present Rh(0)NPs/Fullerene-C60 was tested as catalyst for the reduction of 4-nitrophenol in water. The catalytic reduction  of 4-nitrophenol to 4-aminophenol is very useful process in green chemistry. In general, the nitrophenols are classied as one of the very common organic pollutants that can be found in environmental wastewater and soil, whereas, the aminophenol is highly useful in the preparation of drugs (such as phenacetin, paracetamol, and so on) and it can be used as reducing agent in dye industry and as photographic developers. 37 Hence, research on the development of unique and active catalytic material for the conversion of nitrophenol to useful aminophenol is highly deserved. So far, there are several active catalysts were reported for the reduction of 4-nitrophenol to 4-aminophenol. Very recently, Shen et al., 38 reported catalytic activity of nanocrystalline Au-nanoparticles prepared via facile one-pot ecofriendly process. They found that the prepared bio-Agnanoparticles are highly efficient in the reduction of 4-nitrophenol to 4-aminophenol. Highly stable hollow nanospheres of metal oxide (NiO, CuO, and NiO/CuO) coated with a porous carbon shell (HNSs@C) were successfully prepared by Wu and coworkers. 39 The resultant catalysts (HNSs@C) were found be very active in the reduction of 4-nitrophenol with very high k app and k 0 values. Recently, Baran et al., developed highly efficient Pd-based catalysts for the Suzuki-Miyaura reaction and p-nitrophenol reduction. [40][41][42][43][44][45][46][47] Similarly, Ag(0)@chitosan, 48 Pd-GA/RGO, 49 CA-AuNPs, 50 AgNPs/SiNSs, 51 Ag-P(NIPAM-co-AAm), 52 AgPd-NCs/rGO, 53 CNC/CTAB/Ag, 54 AgNPs/PD/PANFP, 55 Au-Ag@LDH-NPs, 56 FPP/Au, 57 and S-graphene (SG) 58 are also reported. Unfortunately, most of the existing catalytic process show low TOF and k 0 values which are very important for practical use. To our delight, the present Rh(0)NPs/Fullerene-C60 demonstrated very high k app value with excellent TOF (moles of 4-NP converted per mole surface Ni per second) and k 0 values. Interestingly, carbon fullerene-C60 supported Au nanoparticles catalyst (Au/Fullerene-C60) was prepared and used as catalysts for the reduction of 4-nitrophenol by Ko and coworkers. They found that the Au/Fullerene-C60 is active in the 4-nitrophenol reduction, however, the system not attained complete conversion of 4-nitrophenol to 4-aminophenol even aer prolonged reaction time. To the best of our knowledge, this is the rst efficient Rh(0)NP-supported fullerene-C60 catalyst for the reduction reaction reported to date.
At rst, reaction parameters were optimized. The reactions were carried out in aqueous NaBH 4 solution. The catalytic performance of Rh(0)NPs/Fullerene-C60 was evaluated by UVvisible spectroscopy (Fig. 7). Fig. 7a shows the UV-vis spectra of This journal is © The Royal Society of Chemistry 2020 RSC Adv., 2020, 10, 2545-2559 | 2551 4-nitrophenol before and aer the addition of aqueous NaBH 4 . The fresh 4-nitrophenol showed band at 317 nm. Aer the addition of NaBH 4 , the absorption band at 317 nm red-shied to 400 nm due to the formation of 4-nitrophenolate ions. Based on the results, 80 mL of 0.01 M 4-nitrophenol, and 4 mL of 0.015 M aqueous NaBH 4 were opted as optimal reaction conditions. In order to check the catalytic activity of fresh carbon fullerene-C60, 0.1 mg of carbon fullerene-C60 was also used as catalyst for the reduction of 4-nitrophenol (Fig. 7b). As expected, the carbon fullerene-C60 was found to be inactive in the reduction reaction. The stirring reaction mixture with fresh carbon fullerene-C60 as catalyst showed no change in the adsorption maximum at 400 nm even aer 24 h. The results conrm that the fresh carbon fullerene-C60 is inactive in the reduction process and also free from metal impurities. To our delight, the presence of Rh(0)NPs/ Fullerene-C60 rapidly reduces 4-nitrophenol to 4-aminophenol with NaBH 4 . Initially, 1 mg of Rh(0)NPs/Fullerene-C60 was used as catalyst, however, the system converted 4-nitrophenol in less than 10 seconds. Then the amount of Rh(0)NPs/Fullerene-C60 was gradually reduced to 0.001-0.0025 mg. To our delight, very small amount of Rh(0)NPs/Fullerene-C60 (0.0015, 0.002 and 0.0025 mg) was found to be enough for the complete reduction of 4-nitrophenol (Fig. 7d-f). The 0.001 mg of Rh(0)NPs/Fullerene-C60 is not enough for the complete reduction of 4-nitrophenol (Fig. 7c). It can be seen that the 0.0025 mg of Rh(0)NPs/Fullerene-C60 showed rapid reduction of 4-nitrophenol. Surprisingly, the 0.0025 mg of Rh(0)NPs/Fullerene-C60 took only 2 min for the 100% conversion of 4-nitrophenol to 4-aminophenol. To the best of our knowledge, this is the most efficient catalyst reported for the rapid reduction of 4-nitrophenol.  Reaction kinetics was studied for the Rh(0)NPs/Fullerene-C60 catalyzed reduction of 4-nitrophenol. In the present case, the role of fresh carbon fullerene-C60 and the concentration of NaBH 4 were not considered for the kinetic studies. In fact, the carbon fullerene-C60 is not active in the reduction process and an excess amount of NaBH 4 was used. Fig. 8a shows plots of ln [C t /C 0 ] versus reaction time for the reduction of 4-nitrophenol with NaBH 4 over different amounts of Rh(0)NCs/GNPs. The relationship between ln(C t /C 0 ) and time was noticed to be liner with good correlation coefficient (R 2 of about 0.9971) which shows that the Rh(0)NPs/Fullerene-C60 catalyzed reduction of 4-nitrophenol follows pseudo-rst-order reaction kinetics. From the slop of the liner plots, the kinetic reaction rate constant (k app ) was calculated. Form the k app values, reaction rate constant per unit mass (k 0 ) values were calculated using the formula; k 0 ¼ k/M, where Mweight of the metal active site added. Moreover, turn over frequency (TOF, moles of 4-nitrophenol converted per mole surface Rh per minutes) was also calculated. Surprisingly, the k app , k 0 and TOF values are found to be very high when compare to previous results (see Table 1). The k app values for the Rh(0)NPs/Fullerene-C60 catalyzed conversion of 4-nitrophenol to 4-aminophenol were calculated to be 10.75 Â 10 À3 min À1 (0.001 mg), 16.18 Â 10 À3 min À1 (0.0015 mg), 82.14 Â 10 À3 min À1 (0.002 mg) and 132.17 Â 10 À3 min À1 (0.0025 mg). The excellent k 0 value of 4107 Â 10 À3 mg À1 min À1 was calculated for the 0.0025 mg of Rh(0)NPs/Fullerene-C60 catalyzed reduction of 4-nitrophenol. Surprisingly, the present system achieved very high TOF number of 138 min À1 . The reusability of Rh(0)NPs/Fullerene-C60 was also tested in the reduction reaction (Fig. 8b). The Rh(0)NPs/Fullerene-C60 was found to be reusable for several runs without loss in its catalytic ability. The present catalyst showed about 98% conversion of 4nitrophenol to 4-aminophenol even at its 5th use.
The activity of Rh(0)NPs/Fullerene-C60 was compared with previously reported results (Table 1). To the best of our knowledge, k app , k 0 and TOF values are found to be very high when compare to previous results (see Table 1). For example, the NiOnanoparticles supported carbon nanocomposite (NiO/CNP) demonstrated good catalytic activity toward reduction of 4nitrophenol with k 0 value of 1.53 Â 10 À3 mg À1 s À1 whereas the present Rh(0)NPs/Fullerene-C60 showed better k 0 value of 6.9 Â 10 À2 mg À1 s À1 . 35 Meng et al., 59 reported MoS 2 /reduced graphene oxide (1T-MoS 2 /RGO) nanocomposite for the reduction of 4nitrophenol. The 1T-MoS 2 /RGO nanocomposite showed k 0 value of 0.011 Â 10 À3 min À1 g À1 whereas the present catalyst demonstrated better k 0 value. Hareesh and co-workers prepared Ag-Au-rGO nanocomposite and it was used for the reduction of 4-nitrophenol. The Ag-Au-rGO nanocomposite showed k app and TOF values of 34.7 Â 10 À3 s À1 and 2.5 min À1 , respectively. To our delight, the present catalytic system showed k app and TOF values of 132.17 Â 10 À3 min À1 and 138 min À1 , respectively. Similarly, transition metal nanoparticles immobilized human hair or cellulose nanobers supports showed good catalytic activity in the reduction of 4-nitrophenol whereas the present Rh(0)NPs/Fullerene-C60 showed better activity. Table 1 shows the comparison of present Rh(0)NPs/Fullerene-C60 over other reported catalysts. The catalytic activity of Rh(0)NPs/Fullerene-C60 can be compared with the other reported catalysts.
Scheme 2 demonstrates the proposed mechanism for the Rh(0)NPs/Fullerene-C60 catalyzed reduction of 4-nitrophenol to 4-aminophenol with NaBH 4 . Stirring the aqueous mixture of 4nitrophenol, NaBH 4 and Rh(0)NPs/Fullerene-C60 leads to adsorption of nitrophenolate ion (acceptor group) on the surface of Rh(0)NPs/Fullerene-C60 and the donor BH 4À produces active hydrogen atoms on the catalyst surface (as shown in Scheme 2). Subsequently, the formed active hydrogen atoms reduces the adsorbed 4-nitrophenolate ion to 4-aminophenol. Finally, the product 4-aminophenol desorbs from the surface of Rh(0)NPs/Fullerene-C60. The result shows that the Rh(0)NPs/Fullerene-C60 reduces 4-nitrophenol in very short reaction time of just 2 min. This is mainly due to the presence of Rh-nanoparticles with small size in Rh(0)NPs/Fullerene-C60. In Table 1 Comparison of present Rh(0)NPs/Fullerene-C60 over other previously reported catalysts a

Suzuki cross-coupling reaction
Indeed, Suzuki cross-coupling reactions are the prime protocols for the carbon-carbon construction. 65 Particularly, the synthesis of biaryl compounds via Suzuki cross-coupling has become one of the most preferred methods in organic chemistry. [40][41][42][43][44][45][46][47][66][67][68][69][70][71][72] In fact, this reaction is workable with wide range of substrates under mild reaction conditions, and the reaction starting material (boronic acid) is highly sustainable and readily available. Moreover, the catalytic products, biaryl compounds, are vastly useful in the production of various pharmaceuticals, liquid crystals, complex drug molecules, ligands and polymers. 65 68 Other transition metals such as Co, Ni, Cu, Rh, Ru, Ag, Pt and Au are also reported as efficient catalysts for the Suzuki crosscoupling reactions. For instance, Han et al., 69 reported facile preparation of stable Au nanoparticles and their catalytic activity toward Suzuki-Miyaura cross-coupling reaction in water. Alike, boron nitride nanosheet-anchored Pd-Fe coreshell nanoparticles was prepared and used as nanocatalysts for Suzuki-Miyaura coupling reactions by Fu and co-workers. 70 The supported Rh-nanoparticles are demonstrated to be one of the most highly active catalysts for various organic transformations. Gniewek et al., 72 reported Rh(0) nanoparticles supported PVP catalyst (Rh/PVP) for Suzuki-Miyaura reaction and hydrogenation of benzene. Unfortunately, the Rh/PVP showed moderate activity towards the Suzuki-Miyaura reaction. Later, Wang et al., 70 prepared bimetallic Pd-Rh nanocatalyst with tunable morphologies and compositions. The obtained bimetallic Pd-Rh nanocatalyst was found to be highly active toward Suzuki cross-coupling reactions. However, the preparation of bimetallic Pd-Rh nanocatalyst required toxic reducing and capping agent and halide anions (Br À /I À ) as shape control agents. To our delight, the present mono metallic Rh(0) NPs/Fullerene-C60 was found to be highly active for the Suzuki-Miyaura reaction. Surprisingly, no reducing or capping agents were used to control the particle size of Rh. Scheme 2 Proposed mechanism for Rh(0)NPs/Fullerene-C60 catalyzed reduction of 4-nitrophenol to 4-aminophenol in the presence of NaBH 4 . Scheme 3 shows the Rh(0)NPs/Fullerene-C60 catalyzed Suzuki cross-coupling of phenylboronic acid (1a) with various aryl halides. Initially, reaction parameters such as catalyst amount, reaction time, temperature, base and solvent were screened to nd out the most suitable reaction conditions. The coupling of phenylboronic acid (1a) with 4-bromobenzaldehyde (2a) was taken as model reaction. As expected, trace amount of the desired product, biphenyl-4-carbaldehyde (3aa), was obtained in the absence of catalyst. Alike, the fresh carbon fullerene-C60 was also found to be inactive in the crosscoupling reaction. The reaction solvent (1,4-dioxane/water mixture (8 mL of 1,4-dioxane and 2 mL of water)) and time (24 h) were opted as best reaction conditions. Four different amounts of Rh(0)NPs/Fullerene-C60 (1, 2, 2.5 and 3 mg) was used and found that 2.5 mg is enough to achieve the maximum yield of 3aa. Alike, KOH, NaOH and K 2 CO 3 were used as base for the cross-coupling reaction. Among them, KOH was found to be the best one. Reaction temperature was found to play crucial role in the yield of the product. The Rh(0)NPs/Fullerene-C60 gave about 12% of 3aa when the reaction was stirred at room temperature. The optimal reaction temperature was found to be 80 C. Under the optimized reaction conditions, the scope of the catalytic system was extended. The Rh(0)NPs/Fullerene-C60 gave better yield of 87% of the desired product (3aa) whereas Rh/PVP catalyst afford 65% of the desired product. Alike, Rh(0) NPs/Fullerene-C60 catalyzed cross-coupling of 1a and 2b afford biphenyl (3ab) in good yield of 85%. Coupling reaction between 1-bromo-4-nitrobenzene (2c) and phenylboronic acid (1a) yielded 89% of the 4-nitro-1,1 0 -biphenyl (3ac). Similarly, iodobenzene (2d) and its derivatives were also allowed to react with phenylboronic acid (1a) in the presence of Rh(0)NPs/Fullerene-C60. Under the optimized reaction conditions, the reaction between 1a and iodobenzene (2d) gave the desired product (3aa) in excellent 92% yield. The derivatives of iodobenzene, 1-iodo-4nitrobenzene (2e) and 1-iodo-4-methylbenzene (2f), were also reacted with phenylboronic acid (1a) to give 4-nitro-1,1 0biphenyl (3ae, 83%) and 4-methyl-1,1 0 -biphenyl (3af, 61%), respectively. Surprisingly, less reactive chlorobenzene (2g) was allowed to react with 1a to obtain the desired product, biphenyl (3ag). However, the present system showed poor yield of 37% under the optimized reaction conditions. It was found that the Rh(0)NPs/Fullerene-C60 can be reused at least for 4 cycles without signicant loss in its catalytic activity. At 4th cycle, the Rh(0)NPs/Fullerene-C60 gave 73% of the 3aa from the crosscoupling reaction between 1a and 2a. The catalytic performance of the Rh(0)NPs/Fullerene-C60 can be compared with previously reported catalysts such as Pd/Fe 3 O 4 /SiO 2 , 68 Pd-Fe, 70 Rh/PVP, 72 and Pd-Rh nanocatalyst. 71 Scheme 4 depicts the proposed mechanism for the Rh(0) NPs/Fullerene-C60 catalyzed Suzuki-Miyaura reaction of phenylboronic acid with 4-bromobenzaldehyde. The mechanism involves three main steps: oxidative addition, transmetallation and reductive elimination. At rst, the aryl halide species adsorbs on to Rh(0)NPs/Fullerene-C60 through oxidative addi- The present Rh(0)NPs/Fullerene-C60 catalyst is found to be efficient in both reduction of 4-nitrophenol and Suzuki-Miyaura reaction for several reasons: (i) small size of Rhnanoparticles, (ii) good attachment of Rh-nanoparticles with carbon fullerene-C60, (iii) good dispersion of Rh(0)NPs/ Fullerene-C60 in aqueous and organic solvents (due to the presence of small amount of oxygen functional groups) and (iv) high Rh-nanoparticles surface area. In addition, the simple and green preparation method also advantage of this present work.

Conclusions
Highly active Rh(0)NPs/Fullerene-C60 catalyst was successfully obtained by a simple 'mix and heat' method for the very rst time. To our delight, the preparation method involved just water without using any reducing or capping agents. Rh-nanoparticles with mean size of 4.3 nm were uniformly dispersed on the surface of fullerene-C60. The Rh-content in Rh(0)NPs/Fullerene-C60 was determined to be 2.89 wt%. The chemical state of Rhnanoparticles was 0 (metallic Rh), as conrmed by XPS. The crystalline property of Rh(0)NPs/Fullerene-C60 and, good interaction between Rh-nanoparticles and fullerene-C60 were conrmed. The present Rh(0)NPs/Fullerene-C60 exhibited k app , k 0 and TOF values of 82.14 Â 10 À3 min À1 , 4107 Â 10 À3 min À1 and 138 min À1 , respectively, towards the reduction of 4-nitrophenol with NaBH 4 in water. To the best of our knowledge, this is most efficient catalyst for the rapid reduction of 4-nitrophenol reported to date. The utility of the present Rh(0)NPs/Fullerene-C60 towards Suzuki cross-coupling reaction with a variety of functionalized substrates was also demonstrated. The Rh(0)NPs/ Fullerene-C60 demonstrated excellent catalytic activity in Suzuki cross-coupling reaction. Reusability of the Rh(0)NPs/ Fullerene-C60 was also found to be good.

Funding
This research received no external funding.

Conflicts of interest
Authors declare there is no conict of interest.