Issue 56, 2020
From the journal:

Chemical Communications

Fluorescence imaging of hypochlorous acid and peroxynitrite in vitro and in vivo with emission wavelength beyond 750 nm†

Linfang Wang,a   Jing Liu,*a   Shengwei Zhao,b   Hongxing Zhang,a   Yuanqiang Sun,c   Aihua Weid  and  Wei Guo ORCID logo *a  

* Corresponding authors

a School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan 030006, China
E-mail: liujing4203@sxu.edu.cn, guow@sxu.edu.cn

b School of Aerospace Engineering and Applied Mechanics, Tongji University, Shanghai 200092, China

c College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, P. R. China

d Shanxi University Library, Shanxi University, Taiyuan 030006, China

Abstract

A series of near-infrared and photostable Si-oxazine fluorescent dyes was synthesized using a simple three-step procedure, and one of their reduced products, i.e. hydro-Si-oxazine HSiO3, has been utilized to sensitively detect hypochlorous acid and peroxynitrite generation by phagocytes in inflamed and pulmonary fibrosis diseased mice with emission wavelength beyond 750 nm.

Graphical abstract: Fluorescence imaging of hypochlorous acid and peroxynitrite in vitro and in vivo with emission wavelength beyond 750 nm

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Article information

DOI
https://doi.org/10.1039/D0CC02322A
Article type
Communication
Submitted
27 Apr 2020
Accepted
05 Jun 2020
First published
06 Jun 2020

Chem. Commun., 2020,56, 7718-7721

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Fluorescence imaging of hypochlorous acid and peroxynitrite in vitro and in vivo with emission wavelength beyond 750 nm

L. Wang, J. Liu, S. Zhao, H. Zhang, Y. Sun, A. Wei and W. Guo, Chem. Commun., 2020, 56, 7718 DOI: 10.1039/D0CC02322A

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