Trichromatic-emission and dual-ratio semiconducting polymer dots as fluorescent probe for simultaneous quantification of Cu2+ and pH in vitro and in vivo

Qiang Zhang; Junyong Sun; Rongchao Zhang; Xueli Chen; Ningning Chen; Feng Gao

doi:10.1039/D0CC01811B

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Trichromatic-emission and dual-ratio semiconducting polymer dots as fluorescent probe for simultaneous quantification of Cu²⁺ and pH in vitro and in vivo†

Qiang Zhang,^a Junyong Sun,^a Rongchao Zhang,^a Xueli Chen,^a Ningning Chen^a and Feng Gao

*^a

Author affiliations

* Corresponding authors

^a Laboratory of Functionalized Molecular Solids, Ministry of Education, Anhui Key Laboratory of Chemo/Biosensing, Laboratory of Biosensing and Bioimaging (LOBAB), College of Chemistry and Materials Science, Anhui Normal University, Wuhu 241002, P. R. China
E-mail: fgao@mail.ahnu.edu.cn

Abstract

Novel dual-ratio semiconducting polymer dots (Pdots) with trichromatic-emission in the red, green and blue primary-color regions, are designed as lysosome-targeting nanoprobes for the simultaneous detection and multicolor imaging of pH and Cu²⁺ in HeLa cells and zebrafish without cross-interference.

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Article information

DOI: https://doi.org/10.1039/D0CC01811B
Article type: Communication
Submitted: 09 Mar 2020
Accepted: 22 Jun 2020
First published: 22 Jun 2020

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Chem. Commun., 2020,56, 8647-8650

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Trichromatic-emission and dual-ratio semiconducting polymer dots as fluorescent probe for simultaneous quantification of Cu²⁺ and pH in vitro and in vivo

Q. Zhang, J. Sun, R. Zhang, X. Chen, N. Chen and F. Gao, Chem. Commun., 2020, 56, 8647 DOI: 10.1039/D0CC01811B

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