Issue 11, 2020
From the journal:

Chemical Communications

A novel label-free fluorescence assay for dipeptidyl peptidase 4 activity detection based on supramolecular self-assembly†

Yu Zhao, ORCID logo a   Jiawen Zou,a   Yanyan Song,b   Jun Peng,c   Yi Wang ORCID logo *a  and  Yong Bi*b  

* Corresponding authors

a Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, P. R. China
E-mail: mysky@zju.edu.cn

b Department of Neurology, Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai 200081, China
E-mail: aflame@126.com

c Department of Cardiology, the First People's Hospital of Xiaoshan District, Hangzhou, P. R. China

Abstract

This article presents a new label-free fluorescence assay based on supramolecular self-assembly of cucurbit[7]uril and specific peptide Gly-Pro-Phe-Gly for monitoring DPP4 activity in clinical samples. It also displays a good potential application in high-throughput screening of DPP4 inhibitors.

Graphical abstract: A novel label-free fluorescence assay for dipeptidyl peptidase 4 activity detection based on supramolecular self-assembly

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C9CC09053C
Article type
Communication
Submitted
21 Nov 2019
Accepted
06 Jan 2020
First published
07 Jan 2020

Chem. Commun., 2020,56, 1629-1632

Permissions

Request permissions

A novel label-free fluorescence assay for dipeptidyl peptidase 4 activity detection based on supramolecular self-assembly

Y. Zhao, J. Zou, Y. Song, J. Peng, Y. Wang and Y. Bi, Chem. Commun., 2020, 56, 1629 DOI: 10.1039/C9CC09053C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements