Issue 13, 2018

A more reliable synthesis of a Gemini vitamin D analog, a potentially effective chemotherapeutic agent for the treatment of colorectal carcinomas

Abstract

After a serendipitous synthesis of a potentially effective chemotherapeutic agent for the treatment of colorectal carcinomas, a more reliable synthetic method is now described using our building blocks containing stereodefined stereochemistry at C-20.

Graphical abstract: A more reliable synthesis of a Gemini vitamin D analog, a potentially effective chemotherapeutic agent for the treatment of colorectal carcinomas

Supplementary files

Article information

Article type
Research Article
Submitted
03 Apr 2018
Accepted
09 May 2018
First published
11 May 2018

Org. Chem. Front., 2018,5, 2016-2019

A more reliable synthesis of a Gemini vitamin D analog, a potentially effective chemotherapeutic agent for the treatment of colorectal carcinomas

H. Santalla, F. Garrido, G. Gómez and Y. Fall, Org. Chem. Front., 2018, 5, 2016 DOI: 10.1039/C8QO00338F

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