Real-time monitoring of food spoilage in a stable gel platform using a benzothiazole-based fluorescent sensor

Zheng-Xing Zeng; Nan Wang; Yi-Miao Zhang; Guo-Xiang Lan; Hua-Feng Mao; Hou-Qi Ning; Lin-Jia Zhang; Jing-Ting Wen; Zhou-Yu Wang; Xiao-Qi Yu

doi:10.1039/D5CC04141D

Real-time monitoring of food spoilage in a stable gel platform using a benzothiazole-based fluorescent sensor

Zheng-Xing Zeng,†^ac Nan Wang,†*^b Yi-Miao Zhang,^ac Guo-Xiang Lan,^b Hua-Feng Mao,^b Hou-Qi Ning,*^b Lin-Jia Zhang,^ac Jing-Ting Wen,^ac Zhou-Yu Wang

*^ac and Xiao-Qi Yu

^ab

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* Corresponding authors

^a Sichuan Engineering Research Center for Molecular Targeted Diagnostic & Therapeutic Drugs, Xihua University, Chengdu, China
E-mail: zhouyuwang@mail.xhu.edu.cn

^b Food Microbiology Key Laboratory of Sichuan Province, Department of Pharmaceutical Engineering, College of Food and Bioengineering, Xihua University, Chengdu 610039, China
E-mail: wangnan@xhu.edu.cn, ninghouqi@xhu.edu.cn

^c Key Laboratory of High-Performance Scientific Computation, Xihua University, Chengdu, China

Abstract

DBr-Ma, a novel benzothiazole-based fluorescent sensor modified with dicyanide groups, shows exceptional sensitivity and discrimination for biogenic amines (especially spermine/cadaverine), exhibiting a 150-fold sensitivity increase over DBr-CHO. Validated by DFT, HRMS, NMR, and spectroscopy, the gel sensor PD@Ma enables real-time monitoring of seafood spoilage, advancing food safety.

Chemical Communications

Real-time monitoring of food spoilage in a stable gel platform using a benzothiazole-based fluorescent sensor

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Real-time monitoring of food spoilage in a stable gel platform using a benzothiazole-based fluorescent sensor

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