Electrochemical hydro- and seleno-amination of 2,3-dihydrofurans

Abstract

An electrochemical hydro- and seleno-amination of 2,3-dihydrofurans is reported herein, enabling efficient access to tetrahydrofuran-based hemiaminal ether derivatives. Furthermore, this electrochemical strategy is successfully applied for the synthesis of 2-selenonucleoside analogues.

Graphical abstract: Electrochemical hydro- and seleno-amination of 2,3-dihydrofurans

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Article information

Article type
Communication
Submitted
29 Aug 2025
Accepted
10 Nov 2025
First published
11 Nov 2025

Chem. Commun., 2025, Advance Article

Electrochemical hydro- and seleno-amination of 2,3-dihydrofurans

Z. Zhang, L. Wang, G. Zhao, Y. Wang and L. Tian, Chem. Commun., 2025, Advance Article , DOI: 10.1039/D5CC04976H

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