We have developed an upconversion luminescent ratiometric nanoprobe, specifically designed for detection of biothiols with high sensitivity (∼25 nM) at the single-particle level. Using a single-particle localization and rendering method, this nanoprobe enables super-resolution imaging sensing of biothiols within a confined 22 nm space in living cells.
H. Chen, R. Wang, J. Cheng, L. Wang and H. He, Chem. Commun., 2024, 60, 4447 DOI: 10.1039/D3CC06242B
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