Preparation of temperature sensitive molecularly imprinted polymer coatings on nickel foam for determination of ofloxacin in Yellow River water by solid-phase microextraction

Abstract

Nickel foam was firstly used as a solid phase microextraction support to prepare temperature sensitive molecularly imprinted polymers using ofloxacin molecules as the template. The fluorescence intensity could be observed by the naked eye under ultraviolet light after ofloxacin adsorption onto the new materials, which was positively proportional to the adsorbance. After adsorption had occurred, the significantly different fluorescence intensities distinguished the molecularly imprinted polymers from the corresponding non-molecularly imprinted polymers. A detailed evaluation was made by different characterization methods and various adsorption experiments. Finally, the molecularly imprinted polymer on nickel foam was used as an adsorbent in solid phase microextraction, coupled with high performance liquid chromatography, to detect ofloxacin, norfloxacin and enrofloxacin in Yellow River water, obtaining recoveries of 93.2 to 108.3% and limits of quantification of 0.014 to 0.020 μg mL⁻¹.