Microwave assisted novel and regioselective functionalization of imidazopyridines with chromene acetals and β-nitrostyrenes†
Abstract
A facile synthesis of novel functionalized imidazopyridines has been accomplished through the condensation of imidazopyridines with chromene hemiacetals or β-nitro styrenes with high regioselectivity and excellent yields in the presence of a catalytic amount of PTSA or InCl3. In this process, the reaction appears to be very general and suitable for direct functionalization of imidazopyridines. In our present method we successfully achieved regioselectivity.