Issue 98, 2015

MnO2 catalyzed formylation of amines and transamidation of amides under solvent-free conditions

Abstract

A facile and efficient MnO2 catalyzed one-pot protocol for formylation of amine and transamidation of primary and secondary amides by amines has been developed. The present methodology is operationally simple, inexpensive and scalable under solvent free conditions. A series of formylated and transamidated products were synthesized in good to excellent yields.

Graphical abstract: MnO2 catalyzed formylation of amines and transamidation of amides under solvent-free conditions

Supplementary files

Article information

Article type
Paper
Submitted
05 Jul 2015
Accepted
15 Sep 2015
First published
15 Sep 2015

RSC Adv., 2015,5, 80441-80449

Author version available

MnO2 catalyzed formylation of amines and transamidation of amides under solvent-free conditions

S. L. Yedage, D. S. D'silva and B. M. Bhanage, RSC Adv., 2015, 5, 80441 DOI: 10.1039/C5RA13094H

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