Issue 7, 2015

Engineering DNA scaffolds for delivery of anticancer therapeutics

Abstract

Engineering DNA nanostructures with programmability in size, shape and surface chemistry holds tremendous promise in biomedical applications. As an emerging platform for drug delivery, DNA nanostructures have been extensively studied for delivering anticancer therapeutics, including small-molecule drug, nucleic acids and proteins. In this mini-review, current advances in utilizing DNA scaffolds as drug carriers for cancer treatment were summarized and future challenges were also discussed.

Graphical abstract: Engineering DNA scaffolds for delivery of anticancer therapeutics

Article information

Article type
Minireview
Submitted
29 Dec 2014
Accepted
13 Feb 2015
First published
25 Feb 2015

Biomater. Sci., 2015,3, 1018-1024

Engineering DNA scaffolds for delivery of anticancer therapeutics

W. Sun and Z. Gu, Biomater. Sci., 2015, 3, 1018 DOI: 10.1039/C4BM00459K

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