Issue 13, 2014
From the journal:

Journal of Materials Chemistry B

Versatile strained alkyne modified water-soluble AuNPs for interfacial strain promoted azide–alkyne cycloaddition (I-SPAAC)†

Pierangelo Gobbo,a   Zack Mossman,a   Ali Nazemi,a   Aurelia Niaux,a   Mark C. Biesinger,b   Elizabeth R. Gilliesac  and  Mark S. Workentin*a  

* Corresponding authors

a The University of Western Ontario and the Centre for Materials and Biomaterials Research, Richmond Street, London, Ontario, Canada
E-mail: mworkent@uwo.ca
Tel: +1 519-661-2111 ext. 86319

b Surface Science Western, The University of Western Ontario, 999 Collip Circle, London, Ontario, Canada

c Department of Chemical and Biochemical Engineering, The University of Western Ontario, London, Ontario, Canada

Abstract

Versatile water- and organic solvent-soluble AuNPs that incorporate an interfacial strained alkyne capable of efficient pour and mix strain promoted interfacial cycloadditions with azide partners have been synthesized and carefully characterized for the first time. The use of XPS to quantitate the loading of the strained alkyne on the AuNPs is noteworthy. The reactivity towards the interfacial strain promoted azide–alkyne cycloaddition reaction was demonstrated by using azide-decorated polymersomes as bioorthogonal reaction partners.

Graphical abstract: Versatile strained alkyne modified water-soluble AuNPs for interfacial strain promoted azide–alkyne cycloaddition (I-SPAAC)

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3TB21799J
Article type
Communication
Submitted
17 Dec 2013
Accepted
23 Jan 2014
First published
24 Jan 2014

J. Mater. Chem. B, 2014,2, 1764-1769

Author version available

Download author version (PDF)

Permissions

Request permissions

Versatile strained alkyne modified water-soluble AuNPs for interfacial strain promoted azide–alkyne cycloaddition (I-SPAAC)

P. Gobbo, Z. Mossman, A. Nazemi, A. Niaux, M. C. Biesinger, E. R. Gillies and M. S. Workentin, J. Mater. Chem. B, 2014, 2, 1764 DOI: 10.1039/C3TB21799J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements