Kohei Sato, Yoshimitsu Itoh and Takuzo Aida
Chem. Sci., 2014,5, 136-140
DOI:
10.1039/C3SC52449C,
Edge Article
Chiral monomers 1 and 2, carrying C4- and C3-symmetric bowl-shape peptidic macrocycle cores, respectively, undergo supramolecular polymerization in solution via van der Waals and hydrogen bonding interactions. Size-exclusion chromatographic studies, using UV and CD detectors, on the supramolecular copolymerization of their enantiomers demonstrated that these monomers are the first chiral macrocycles that polymerize enantioselectively with a strong preference for chiral self-sorting.