Issue 6, 2013

A highly efficient BF3·Et2O-catalysed intramolecular [3+2] cycloaddition for the synthesis of 3,4-dihydrobenzopyrano[3,4-c]pyrazoles

Abstract

A highly efficient BF3·Et2O catalysed intramolecular [3+2] cycloaddition of tosylhydrazone with alkyne has been developed, and a variety of potentially bioactive 1,8-disubstituted-3,4-dihydrobenzopyrano[3,4-c]pyrazoles 7 were obtained with good to excellent yields of up to 93%.

Graphical abstract: A highly efficient BF3·Et2O-catalysed intramolecular [3+2] cycloaddition for the synthesis of 3,4-dihydrobenzopyrano[3,4-c]pyrazoles

Supplementary files

Article information

Article type
Communication
Submitted
03 Sep 2012
Accepted
05 Dec 2012
First published
06 Dec 2012

RSC Adv., 2013,3, 1687-1690

A highly efficient BF3·Et2O-catalysed intramolecular [3+2] cycloaddition for the synthesis of 3,4-dihydrobenzopyrano[3,4-c]pyrazoles

W. Wang, Y. Feng, W. Gao, X. Luo and W. Deng, RSC Adv., 2013, 3, 1687 DOI: 10.1039/C2RA22025C

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