The challenging coupling of 10-halobenzo[h]quinolines with ortho-substituted aryl boronic acids has been achieved using Pd(OAc)2/P(O)Ph3 as the catalytic system. High yields were obtained for diversely functionalised substrates under mild reaction conditions.
![Graphical abstract: Synthesis of sterically encumbered C10-arylated benzo[h]quinolines using ortho-substituted aryl boronic acids](/en/Image/Get?imageInfo.ImageType=GA&imageInfo.ImageIdentifier.ManuscriptID=C2OB26806J&imageInfo.ImageIdentifier.Year=2013)
M. Weimar and M. J. Fuchter, Org. Biomol. Chem., 2013, 11, 31 DOI: 10.1039/C2OB26806J
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