Issue 1, 2013
From the journal:

Nanoscale

Cholesterol – a biological compound as a building block in bionanotechnology

Leticia Hosta-Rigau,a   Yan Zhang,ab   Boon M. Teo,a   Almar Postmac  and  Brigitte Städler*a  

* Corresponding authors

a iNANO, Aarhus University, Aarhus, Denmark
E-mail: bstadler@inano.au.dk
Tel: +45 8715 6668

b State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Material Science and Engineering, Donghua University, Shanghai 201620, People's Republic of China

c CSIRO Materials Science and Engineering, Ian Wark Laboratory, Bayview Ave, Clayton, Victoria 3168, Australia

Abstract

Cholesterol is a molecule with many tasks in nature but also a long history in science. This feature article highlights the contribution of this small compound to bionanotechnology. We discuss relevant chemical aspects in this context followed by an overview of its self-assembly capabilities both as a free molecule and when conjugated to a polymer. Further, cholesterol in the context of liposomes is reviewed and its impact ranging from biosensing to drug delivery is outlined. Cholesterol is and will be an indispensable player in bionanotechnology, contributing to the progress of this potent field of research.

Graphical abstract: Cholesterol – a biological compound as a building block in bionanotechnology

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Article information

DOI
https://doi.org/10.1039/C2NR32923A
Article type
Feature Article
Submitted
26 Sep 2012
Accepted
31 Oct 2012
First published
05 Nov 2012

Nanoscale, 2013,5, 89-109

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Cholesterol – a biological compound as a building block in bionanotechnology

L. Hosta-Rigau, Y. Zhang, B. M. Teo, A. Postma and B. Städler, Nanoscale, 2013, 5, 89 DOI: 10.1039/C2NR32923A

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