Issue 1, 2013
From the journal:

Chemical Communications

Long genomic DNA amplicons adsorption onto unmodified gold nanoparticles for colorimetric detection of Bacillus anthracis

Hua Deng,a   Xu Zhang,a   Anil Kumar,a   Guozang Zou,a   Xiaoning Zhang*b  and  Xing-Jie Liang*a  

* Corresponding authors

a CAS Key Laboratory for Biological Effects of Nanomaterials & Nanosafety, National Center for Nanoscience and Technology, 11 Beiyijie, Beijing 100190, Zhongguancun, China
E-mail: liangxj@nanoctr.cn
Fax: +86 10-62656765
Tel: +86 10-82545569

b School of Medicine, Tsinghua University, China
E-mail: drugman@tsinghua.edu.cn

Abstract

Unmodified gold nanoparticles (GNPs) can be wrapped with long genomic single- and double-stranded DNA (ssDNA and dsDNA) molecules produced by asymmetric polymerase chain reaction (As-PCR). More importantly, the DNA–Au interaction can be utilized for colorimetric detection of a specific nucleic acid sequence in clinical samples.

Graphical abstract: Long genomic DNA amplicons adsorption onto unmodified gold nanoparticles for colorimetric detection of Bacillus anthracis

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Article information

DOI
https://doi.org/10.1039/C2CC37037A
Article type
Communication
Submitted
28 Sep 2012
Accepted
26 Oct 2012
First published
26 Oct 2012

Chem. Commun., 2013,49, 51-53

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Long genomic DNA amplicons adsorption onto unmodified gold nanoparticles for colorimetric detection of Bacillus anthracis

H. Deng, X. Zhang, A. Kumar, G. Zou, X. Zhang and X. Liang, Chem. Commun., 2013, 49, 51 DOI: 10.1039/C2CC37037A

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