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Abstract | Cited by

We report the design, synthesis and evaluation of a novel macromolecular membrane permeabilizer displaying geminally substituted crown-ethers (18-crown-6) on every third carbon alongside the backbone. The polymer has a rather high affinity with potassium as well as permeabilization properties towards K+, Na+ and Ca2+, including single-channel behavior.

Graphical abstract: A polymeric membrane permeabilizer displaying densely packed arrays of crown ether lateral substituents

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