Issue 8, 2012

Synthesis of 2-amino-imidazoles, purines, and benzoxazolamines through DIB oxidation

Abstract

A wide range of fused 2-amino-imidazoles and 2-amino-benzoxazoles can be prepared in one-pot under very mild conditions from 1,2-diamino-arenes or 2-amino-phenols and Vilsmeier reagents. The oxidation proceeds using diacetoxy-iodobenzene (DIB) and is tolerant to different functionalities.

Graphical abstract: Synthesis of 2-amino-imidazoles, purines, and benzoxazolamines through DIB oxidation

Supplementary files

Article information

Article type
Communication
Submitted
17 Jan 2012
Accepted
22 Feb 2012
First published
24 Feb 2012

RSC Adv., 2012,2, 3261-3264

Synthesis of 2-amino-imidazoles, purines, and benzoxazolamines through DIB oxidation

J. Andrez, RSC Adv., 2012, 2, 3261 DOI: 10.1039/C2RA20101A

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