Issue 11, 2012
From the journal:

RSC Advances

Synthesis of bivalent neogalactolipids via modified Staudinger reaction†

Ekaterina A. Ivanova,a   Mikhail A. Maslov,*a   Nina G. Morozova,a   Galina A. Serebrennikovaa  and  Vladimir V. Chupinab  

* Corresponding authors

a M. V. Lomonosov Moscow State University of Fine Chemical Technology, 86 Vernadskiy ave., Moscow, Russian Federation
E-mail: mamaslov@mail.ru
Fax: +7(495)9368901
Tel: +7(495)9368901

b Shemyakin-Ovchinnikov Institute of bioorganic chemistry RAS, 16/10 Ul. Miklukho-Maklaya, Moscow, Russian Federation
E-mail: chupin@nmr.ru
Fax: +7(495)3355033
Tel: +7(495)3352733

Abstract

The synthesis of bivalent galactose-containing neutral lipids for the development of a targeted gene delivery system to the hepatocytes has been described. For introducing galactosyl ligands into the lipid molecule, a convenient approach based on modified Staudinger reaction was used.

Graphical abstract: Synthesis of bivalent neogalactolipids via modified Staudinger reaction

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Article information

DOI
https://doi.org/10.1039/C2RA01356H
Article type
Communication
Submitted
25 Dec 2011
Accepted
19 Mar 2012
First published
20 Mar 2012

RSC Adv., 2012,2, 4600-4602

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Synthesis of bivalent neogalactolipids via modified Staudinger reaction

E. A. Ivanova, M. A. Maslov, N. G. Morozova, G. A. Serebrennikova and V. V. Chupin, RSC Adv., 2012, 2, 4600 DOI: 10.1039/C2RA01356H

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