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Abstract | Cited by

Using CuBr2 as an additive, the Pd-catalyzed intermolecular C–H–C–H cross-coupling between benzoxazoles and unactivated simple arenes has been developed. This protocol provides a straightforward approach for the biological activity of 2-arylbenzoxazole derivatives.

Graphical abstract: Palladium-catalyzed direct arylation of benzoxazoles with unactivated simple arenes

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