Issue 10, 2012
From the journal:

Chemical Communications

Measuring rapid kinetics by a potentiometric method in droplet-based microfluidic devices†‡

Zuoyan Han,a   Yuen Yan Chang,a   Shannon Wing Ngor Aub  and  Bo Zheng*a  

* Corresponding authors

a Department of Chemistry, The Chinese University of Hong Kong, Shatin, Hong Kong
E-mail: bozheng@cuhk.edu.hk
Fax: +852 26035057
Tel: +852 26096261

b Department of Biochemistry, The Chinese University of Hong Kong, Shatin, Hong Kong

Abstract

Droplets containing RNA and Mg2+ were generated in microfluidic channels. By integrating a group of pneumatic valves and phase separation channels in the microfluidic system, the rapid RNA–Mg2+ binding kinetics was studied by measuring the Mg2+ ion concentration using an ion-selective electrode.

Graphical abstract: Measuring rapid kinetics by a potentiometric method in droplet-based microfluidic devices

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Article information

DOI
https://doi.org/10.1039/C1CC12383A
Article type
Communication
Submitted
24 Apr 2011
Accepted
24 Jun 2011
First published
08 Jul 2011

Chem. Commun., 2012,48, 1601-1603

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Measuring rapid kinetics by a potentiometric method in droplet-based microfluidic devices

Z. Han, Y. Y. Chang, S. W. N. Au and B. Zheng, Chem. Commun., 2012, 48, 1601 DOI: 10.1039/C1CC12383A

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