Issue 71, 2024
From the journal:

Chemical Communications

A novel NIR-II fluorescent probe for hydrogen peroxide detection in drug-induced liver injury†

Huiyu Chen,‡a   Hui Zhou, ORCID logo ‡*a   Xinyue Zhang,a   Yancheng Ding,a   Xiaolong Zhang,a   Qinqin Xu,a   Ben Wang,a   Chao Yin ORCID logo *a  and  Quli Fan ORCID logo a  

* Corresponding authors

a State Key Laboratory of Organic Electronics and Information Displays, Jiangsu Key Laboratory for Biosensors, Institute of Advanced Materials (IAM), Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), School of Materials Science and Engineering, Nanjing, Jiangsu, China
E-mail: iamhzhou@njupt.edu.cn, iamcyin@njupt.edu.cn

Abstract

The synthesis of H2O2-activatable small molecules in the second near-infrared (NIR-II) window remains challenging. We present the NIR-II probe Z-1065 for real-time detection of H2O2. Z-1065 demonstrates high sensitivity and selectivity towards H2O2in vitro and effectively monitors H2O2 generation in drug-induced liver injury (DILI) mouse models.

Graphical abstract: A novel NIR-II fluorescent probe for hydrogen peroxide detection in drug-induced liver injury

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/D4CC03512G
Article type
Communication
Submitted
14 Jul 2024
Accepted
12 Aug 2024
First published
13 Aug 2024

Chem. Commun., 2024,60, 9618-9621

Permissions

Request permissions

A novel NIR-II fluorescent probe for hydrogen peroxide detection in drug-induced liver injury

H. Chen, H. Zhou, X. Zhang, Y. Ding, X. Zhang, Q. Xu, B. Wang, C. Yin and Q. Fan, Chem. Commun., 2024, 60, 9618 DOI: 10.1039/D4CC03512G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements