We present a triple-mode nanosensor platform for nucleic acid detection utilizing fluorescence anisotropy and Förster resonance energy transfer (FRET) strategies. The self-assembled nanoprobes serve as mass amplifiers, nanoquenchers, or nanodonors, exhibiting high FRET efficiencies (64.4–86.5%) and demonstrating excellent detection capabilities in DNA and microRNA analysis.
C. Guo, E. Cui, M. Wang, X. Liu, Y. Yu, X. Xie and D. Yang, Chem. Commun., 2024, 60, 4942 DOI: 10.1039/D4CC01327A
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